Mendoza, Argentina

It’s one of the world’s great wine capitals, and like any great vintage, Mendoza is only getting better with age. Start your tasting tour in the Uco Valley, where Casa de Uco’s vineyard-view eco-villas will debut this year. Head down the road to to Vines of Mendoza’s Winemakers’ Village for small-production wines from the likes of Corazón del Sol and SuperUco, and to dine at winery Bodega Monteviejo, where renowned Spanish chef Nadia Harón cooks up Mediterranean-tinged fare inspired by the wines. In Maipú, wineries like Club Tapiz and Trapiche are giving visitors a true taste of the local terroir, using produce grown on the vineyard grounds in their restaurants. Back in town, plot your return trip over a pie at Francis Mallman’s year-old pizzeria, Orégano. With new direct flights from Lima, Panama City, Rio de Janeiro, and São Paulo, and low-cost carrier Norwegian Air plotting dozens of new routes, tacking a Mendoza stop on to your next South American itinerary will be a breeze.